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The European Union and the United States have strong disagreements over the EU's regulation of genetically modified food. The US claims these regulations violate free trade agreements, the EU counter-position is that free trade is not truly free without informed consent.
In Europe, a series of unrelated food crises during the 1990s created consumer apprehension about food safety in general, eroded public trust in government oversight of the food industry, and left some consumers unwilling to consider "science" to be a guarantee of quality.
This has further fueled widespread () public concern about genetically modified organisms (GMO), in terms of potential environmental protection (in particular biodiversity), health, and safety of consumers. Critics of GM foods contend that there is evidence that the cultivation of genetically modified plants may lead to environmental changes. Directives such as directive 2001/18/EC were designed to require authorisation for the placing GMO on the market, in accordance with the precautionary principle. (see also Tax, tariff and trade).
Many European consumers are demanding the right to make an informed choice about whether or not to consume GMO foods. Some polls indicate that some Americans would also like labeling, but it has not become a major issue. New EU regulations are expected to require strict labeling and traceability of all food and animal feed containing more than 0.5 percent GM ingredients. Also Codex Alimentarius published a document to safe guard the GM food in 2003 and further compliances need to be made if the GM food is for the purpose of exporting and importing .
A 2003 survey by the Pew Research Center found that a majority of people in all countries surveyed felt that GM foods were "bad". The lowest scores were in the US and Canada, where 55% and 63% (respectively) were against it, while the highest were in Germany and France with 81% and 89% disapproving. The survey also showed a strong tendency for women to be more opposed to GM foods than men.
In 2002, Oregon Ballot measures gave voters in that state one of the first opportunities in the United States to directly address that issue. The measure, which would have required the labeling of genetically engineered foods, failed to pass by a ratio of 7 to 3.
Friedrich-Wilhelm Graefe zu Baringdorf, member of the German Green Party and vice president of the Landwirtschaftsausschuss (committee of agriculture) of the European Commission said on the 1 July 2003: "In America 55% of the consumers are against GM food and 90% in favor of a clear labeling."

